Reduced GABAergic inhibition of kidney - related PVN neurons in streptozotocin - 1 treated type 1 diabetic mouse
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چکیده
Reduced GABAergic inhibition of kidney-related PVN neurons in streptozotocin1 treated type 1 diabetic mouse 2 3 Yanyan Jiang, Hong Gao, Amanda M. Krantz, Andrei V. Derbenev, Andrea 4 Zsombok 5 6 7 Neuroscience Program, School of Science and Engineering, Tulane University and 8 Department of Physiology, School of Medicine, Tulane University, New Orleans LA, 9 USA 10 11 12 Abbreviated title: Synaptic plasticity of PVN neurons in diabetes 13 14 Corresponding author: 15 Andrea Zsombok, PhD 16 Department of Physiology and Medicine, Endocrinology Section 17 School of Medicine 18 Tulane University 19 1430 Tulane Ave., SL-39 20 New Orleans, LA 70112 21 Telephone: (504) 988-2597, Fax: (504) 988-2675 22 e-mail: [email protected] 23 24 25 Articles in PresS. J Neurophysiol (August 21, 2013). doi:10.1152/jn.00013.2013
منابع مشابه
Reduced GABAergic inhibition of kidney-related PVN neurons in streptozotocin-treated type 1 diabetic mouse.
Activity of presympathetic neurons in the paraventricular nucleus (PVN) of the hypothalamus is known to play an important role in the regulation of sympathetic outflow. Sympathetic overactivity is associated with many pathophysiological conditions such as diabetes mellitus and hypertension; however, the underlying synaptic mechanisms are poorly understood. In this study, we examined the GABAerg...
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